CETP Inhibition as a novel treatment to remove pathogen lipids and improve survival in sepsis

The major goal of this project is to investigate genetic mechanisms that determine high-density lipoprotein particle (HDL) levels in sepsis. We have discovered a gene, called CETP, that appears to play a very important role in determining HDL levels during sepsis, and thereby contributes to whether or not a patient will survive the episode of sepsis. 

Funder / Sponsor
CIHR
Project Status
Active/Ongoing
Lead Institution
St Paul's Hospital
Collaborators
Keith Walley
Jim Russell
Collaborator (No Profile)
Liam Brunham
Trainee (no profile)
N/A

Researchers

John Boyd
  • Management

First Nations land acknowledegement

Action on Sepsis operates on the traditional, ancestral, and unceded territory of the Coast Salish peoples — xʷməθkʷəy̓əm (Musqueam), Sḵwx̱wú7mesh (Squamish), and Səl̓ílwətaʔ/Selilwitulh (Tsleil-Waututh) Nations. We invite everyone to reflect on the traditional territories and land that they currently work and live on.

Action on Sepsis Research Cluster

UBC Research Excellence Clusters is a joint initiative of the Provost and Vice-President, Academic and the Vice-President, Research and Innovation.
Clusters receive financial support from UBC’s Excellence Funds.

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