The major goal of this project is to investigate genetic mechanisms that determine high-density lipoprotein particle (HDL) levels in sepsis. We have discovered a gene, called CETP, that appears to play a very important role in determining HDL levels during sepsis, and thereby contributes to whether or not a patient will survive the episode of sepsis.
CETP Inhibition as a novel treatment to remove pathogen lipids and improve survival in sepsis
Funder / Sponsor
St Paul's Hospital
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