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Current Research Projects

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Title Lead Researcher Institution Research Area(s)
Acute cardiac, kidney and lung injury in COVID-19 Jim Russell St Paul's Hospital Prevention, Population and Public Health
AMRIC: Antimicrobial resistance in intensive care Srinivas Murthy University of British Columbia, BC Children's Hospital Research Institute Prevention, Population and Public Health
An in vitro neonatal gut model to understand necrotizing enterocolitis Pascal Lavoie BC Children's Hospital Diagnosis
BC COVID Vaccine Immunity Evaluation Manish Sadarangani UBC/BCCHR Prevention, Population and Public Health
Canadian treatments for COVID-19: SOLIDARITY Srinivas Murthy University of British Columbia Management
CETP Inhibition as a novel treatment to remove pathogen lipids and improve survival in sepsis John Boyd St Paul's Hospital Management
COVID-19 vaccine initiative Wilfred Jefferies University of British Columbia Prevention, Population and Public Health
COVID-19: Improving the evidence to treat an emerging infection through observational studies and a randomized trial Srinivas Murthy University of British Columbia Management
Development of a vaccine platform for prevention of antibiotic-resistant Gram-negative infections Manish Sadarangani Vaccine Evaluation Center Prevention, Population and Public Health
Diabetes and sepsis Jim Russell St Paul's Hospital Prevention, Population and Public Health
Digital virtual support of cases and contacts to novel coronavirus (COVID-19): readiness and knowledge sharing for global outbreaks (WelTel PHM) Richard Lester University of British Columbia Prevention, Population and Public Health
Ensuring optimal protection from MenB vaccines Manish Sadarangani UBC/BCCHR Prevention, Population and Public Health
Epinephrine in pediatric shock Srinivas Murthy University of British Columbia Management
Evaluating an automated blood culture system at a hospital in Botswana David Goldfarb University of British Columbia Diagnosis
Evaluation of the BC pneumoccal immunization program in children at increased risk of pneumococcal disease Manish Sadarangani Vaccine Evaluation Center Prevention, Population and Public Health
Global control of HPV-related diseases and cancer Gina Ogilvie University of British Columbia Prevention, Population and Public Health
Guidelines for severe COVID and management of sepsis Niranjan "Tex" Kissoon Global Sepsis Alliance Management,  Prevention, Population and Public Health
Healthcare worker perspectives of COVID-19 Srinivas Murthy University of British Columbia Management,  Prevention, Population and Public Health
Host response mediators in coronavirus infection Jim Russell St .Paul's Hospital Management
Host response mediators in coronavirus infection – ARBs CORONA II Jim Russell St Paul's Hospital Management
Identifying and evaluating the role of endotypes in sepsis diagnosis and treatment Bob Hancock University of British Columbia Diagnosis,  Management
Identifying molecular mechanisms that regulate sepsis Wilfred Jefferies University of British Columbia Diagnosis
IMPACT: National program of hospital-based active surveillance for vaccine-associated adverse events and selected infections Manish Sadarangani Vaccine Evaluation Center Prevention, Population and Public Health
Implementation of provincial pediatric sepsis screening and management tools Kit Johnson, Garth Meckler University of British Columbia Management,  Prevention, Population and Public Health
Improving sepsis outcomes with anti-PCSK9 monoclonal antibody therapy Keith Walley St Paul's Hospital Management
Improving the early diagnosis of sepsis Pascal Lavoie BC Children's Hospital Diagnosis
Integrating a neonatal healthcare package for Malawi David Goldfarb University of British Columbia Management,  Prevention, Population and Public Health
Investigating the sepsis endotype leading to death in COVID-19 patients Bob Hancock University of British Columbia Diagnosis
Molecular epidemiology and immune responses to Klebsiella infectionin children to improve understanding of pathogenesis and inform development of a Klebsiella vaccine. Manish Sadarangani BC Children's Hospital Research Institute Prevention, Population and Public Health
MOSAIC: Mix and match of the second COVID-19 vaccine dose for Safety and ImmunogeniCity Manish Sadarangani UBC/BCCHR Prevention, Population and Public Health
Multisystem inflmmatory syndrome in children with COVID-19 Niranjan "Tex" Kissoon Global Sepsis Alliance Management
OptiDev: Validating a culturally appropriate, e-tool for assessing neurodevelopment post-sepsis Liisa Holsti University of British Columbia Management,  Prevention, Population and Public Health
Optimizing varicella immunization in children with solid organ transplants to prevent disease and improve long-term health Manish Sadarangani Vaccine Evaluation Center Prevention, Population and Public Health
Pediatric Sepsis Data CoLab Niranjan "Tex" Kissoon BC Children's Hospital Diagnosis,  Management,  Prevention, Population and Public Health
Pediatric sepsis definition & guidelines Niranjan "Tex" Kissoon Global Sepsis Alliance Management
Pediatric sepsis definitions Cheryl Peters BC Children's Hospital Diagnosis,  Management
Pediatric Sepsis Screening at Surrey Memorial Hospital Kit Johnson Child Health BC / Fraser Health
Prediction of mortality in children admitted to the pediatric intensive care unit Matthias Görges BC Children's Hospital Management
Priority setting and resource allocation in health care Craig Mitton University of British Columbia Prevention, Population and Public Health
REMAP-CAP: A randomised,embedded, multi-factorial, adaptive platform trial for community-acquired pneumonia Srinivas Murthy Oxford University Management
Role of epigenetics in post-sepsis syndrome Bob Hancock University of British Columbia Management
Sepsis screening implementation planning at BC Children's Hospital Garth Meckler University of British Columbia Management,  Prevention, Population and Public Health
Seroprevalence of SARS-CoV-2 among African Canadians: Clinical and Epidemiological Correlates Upton Allen SickKids Hospital Prevention, Population and Public Health
Severe acute respiratory infections (SARI) in Pakistan Srinivas Murthy University of British Columbia Management
Sex determinants in coronavirus infection Jim Russell St Paul's Hospital Management
Smart Discharges Matthew Wiens Walimu; BC Children's Hospital Prevention, Population and Public Health
Smart Triage Mark Ansermino BC Children's Hospital Management
SONRIS: Sepsis outcome network to improve survival John Boyd St Paul's Hospital Management,  Prevention, Population and Public Health
SPRINT-SARI: Short PeRiod IncideNce sTudy of Severe Acute Respiratory Infection Srinivas Murthy University of British Columbia Management
Subproject of Canadian Immunization Research Network II Epidemiology of invasive pneumococcal disease, effectiveness of new generation conjugate vaccines and potential of future vaccines in Canada Manish Sadarangani UBC/BCCHR Prevention, Population and Public Health
Time-Series Analysis of Pediatric Sepsis at BC Children's Hospital in relation to the COVID-19 Pandemic Srinivas Murthy University of British Columbia Prevention, Population and Public Health
Tracking pediatric emergency department visits during a pandemic Ran Goldman BC Children's Hospital Prevention, Population and Public Health
Using GWAS to identify genes and pathways important in clinical outcomes of sepsis. Keith Walley St Paul's Hospital Diagnosis,  Management
Vital Video: a system to identify critically ill infants using video monitoring in Malawi Guy Dumont University of British Columbia Diagnosis
WelTel mHealth Platform Richard Lester University of British Columbia Prevention, Population and Public Health
WOMANPOWER: The immunogenicity of combined pertussis-containing vaccine (Tdap) for HIV-infected pregnant women and their newborns Manish Sadarangani Vaccine Evaluation Center Prevention, Population and Public Health