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Current Research Projects

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Title Lead Researcher Institution Research Area(s)
Assessment of cumulative incidence and factors associated with hospital re-admission and severe maternal morbidity after delivery discharge in British Columbia Marianne Vidler University of British Columbia Prevention, Population and Public Health
CETP Inhibition as a novel treatment to remove pathogen lipids and improve survival in sepsis John Boyd St Paul's Hospital Management
Characterizing the molecular epidemiology of Klebsiella infection in children to inform development of a vaccine Manish Sadarangani Vaccine Evaluation Centre at BCCH, Uganda Virus Research Institute Prevention, Population and Public Health
Developing an educational pamphlet on post-sepsis syndrome to improve care for sepsis survivors Marie-Maxime Bergeron, Kristine Russell, Kristin MacDonald, Susan Korstad University of British Columbia Prevention, Population and Public Health
Development of novel pediatric sepsis criteria Pediatric Sepsis Definition Taskforce Society for Critical Care Medicine Diagnosis
Ensuring optimal protection from MenB vaccines Manish Sadarangani UBC/BCCHR Prevention, Population and Public Health
Epidemiology of invasive pneumococcal disease, effectiveness of new generation conjugate vaccines and potential of future vaccines in Canada Manish Sadarangani Canadian Immunization Research Network Prevention, Population and Public Health
Epinephrine in pediatric shock Srinivas Murthy University of British Columbia Management
Evaluating an automated blood culture system at a hospital in Botswana David Goldfarb University of British Columbia Diagnosis
Global control of HPV-related diseases and cancer Gina Ogilvie University of British Columbia Prevention, Population and Public Health
Guidelines for severe COVID and management of sepsis Niranjan "Tex" Kissoon Global Sepsis Alliance Management,  Prevention, Population and Public Health
Healthcare worker perspectives of COVID-19 Srinivas Murthy University of British Columbia Management,  Prevention, Population and Public Health
Host response mediators in coronavirus infection – ARBs CORONA II Jim Russell St Paul's Hospital Management
Identifying and evaluating the role of endotypes in sepsis diagnosis and treatment Bob Hancock University of British Columbia Diagnosis,  Management
Identifying molecular mechanisms that regulate sepsis Wilfred Jefferies University of British Columbia Diagnosis
IMPACT: National program of hospital-based active surveillance for vaccine-associated adverse events and selected infections Manish Sadarangani Vaccine Evaluation Center Prevention, Population and Public Health
Implementation of provincial pediatric sepsis screening and management tools at emergency departments in BC Garth Meckler Child Health BC University of British Columbia Management,  Prevention, Population and Public Health
Improving sepsis outcomes with anti-PCSK9 monoclonal antibody therapy Keith Walley St Paul's Hospital Management
Improving the early diagnosis of sepsis Pascal Lavoie BC Children's Hospital Diagnosis
Integrating a neonatal healthcare package for Malawi David Goldfarb University of British Columbia Management,  Prevention, Population and Public Health
Investigating the sepsis endotype leading to death in COVID-19 patients Bob Hancock University of British Columbia Diagnosis
MOSAIC: Mix and match of the second COVID-19 vaccine dose for Safety and ImmunogeniCity Manish Sadarangani Joanne Langley Clinical Trials Network of the Canadian Immunization Network (CIRN) Prevention, Population and Public Health
Multisystem inflmmatory syndrome in children with COVID-19 Niranjan "Tex" Kissoon Global Sepsis Alliance Management
OptiDev: Validating a culturally appropriate, e-tool for assessing neurodevelopment post-sepsis Liisa Holsti University of British Columbia Management,  Prevention, Population and Public Health
Pediatric Outcome Improvement through Coordination of Research Networks (POPCORN) Caroline Quach Centre hospitalier universitaire Sainte-Justine Prevention, Population and Public Health
Pediatric Sepsis Data CoLab Niranjan "Tex" Kissoon BC Children's Hospital Diagnosis,  Management,  Prevention, Population and Public Health
Pediatric sepsis definitions Cheryl Peters BC Children's Hospital Diagnosis,  Management
Priority setting and resource allocation in health care Craig Mitton University of British Columbia Prevention, Population and Public Health
REMAP-CAP: A randomised,embedded, multi-factorial, adaptive platform trial for community-acquired pneumonia Srinivas Murthy Oxford University Management
Role of epigenetics in post-sepsis syndrome Bob Hancock University of British Columbia Management
Seroprevalence of SARS-CoV-2 among African Canadians: Clinical and Epidemiological Correlates Upton Allen SickKids Hospital Prevention, Population and Public Health
Severe acute respiratory infections (SARI) in Pakistan Srinivas Murthy University of British Columbia Management
Smart Discharges Matthew Wiens Walimu; BC Children's Hospital Prevention, Population and Public Health
Smart Triage Mark Ansermino, Niranjan "Tex" Kissoon BC Children's Hospital Management
SONRIS: Sepsis outcome network to improve survival John Boyd St Paul's Hospital Management,  Prevention, Population and Public Health
SPRINT-SARI: Short PeRiod IncideNce sTudy of Severe Acute Respiratory Infection Srinivas Murthy University of British Columbia Management
The SPRING study: Severe acute resPiratory syndrome-Related coronavirus 2 prevalence In children and youNG adults in British Columbia Manish Sadarangani Vaccine Evaluation Centre and BC Children's Hospital Research Institute Prevention, Population and Public Health
Time-series analysis of pediatric sepsis at BC Children's Hospital in relation to the COVID-19 pandemic Srinivas Murthy University of British Columbia Prevention, Population and Public Health
Using aerobic exercise to improve health outcomes for sepsis survivors John Boyd Centre for Heart Lung Innovation Prevention, Population and Public Health
Using GWAS to identify genes and pathways important in clinical outcomes of sepsis. Keith Walley St Paul's Hospital Diagnosis,  Management
Validating a molecular approach for pathogen detection to understand the epidemiology of sepsis in young infants treated at health facilities in low-resource settings Matthew Wiens, Pascal Lavoie BC Children's Hospital Research Institute Diagnosis
Vital Video: a system to identify critically ill infants using video monitoring in Malawi Guy Dumont University of British Columbia Diagnosis
WelTel mHealth Platform Richard Lester University of British Columbia Prevention, Population and Public Health
What Families Think and Do? A survey for families visiting the pediatric emergency departmentt Ran Goldman BC Children's Hospital Prevention, Population and Public Health
WHO Solidarity Trials to identify life-saving treatments for COVID-19 Srinivas Murthy University of British Columbia Management
WOMANPOWER: The immunogenicity of combined pertussis-containing vaccine (Tdap) for HIV-infected pregnant women and their newborns Manish Sadarangani Vaccine Evaluation Center Prevention, Population and Public Health